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Unite Against Ankylosing spondylitis - AS
Cancer
Sat Jul 22 2023
Ankylosing spondylitis (AS) is a severe, inflammatory ailment of the axial spine. Progressive spinal stiffness and chronic back pain are the most prevalent features of this illness. There is the involvement of the sacroiliac joints, spine, peripheral joints, entheses, and digits are quite characteristic. Physiologically impaired spinal movement, hip pain, posterior pain, postural abnormalities, peripheral arthritis, dactylitis, and enthesitis are generally related to ankylosing spondylitis.
This type of activity is instrumental in reviewing the assessment and management of ankylosing spondylitis and reflects the inter-professional team’s role in assessing and enhancing the care of patients suffering from this condition. The objectives are given below:
- Recognise the aetiology of ankylosing spondylitis.
- Mention the workup of a patient with ankylosing spondylitis
- Going through the management options which are available for ankylosing spondylitis.
- Put the inter-professional team strategies in a nutshell for enhancing care and outcomes in patients with ankylosing spondylitis.
HLA-B27 (Human Leukocyte Antigen B27) is a genetic marker that plays a significant role in the development of Ankylosing Spondylitis (AS).
It's important to understand that HLA-B27 testing alone cannot be used to diagnose Ankylosing Spondylitis, as not all individuals with HLA-B27 positivity develop the condition. Similarly, some individuals with Ankylosing Spondylitis do not have the HLA-B27 marker. Thus, the diagnosis of Ankylosing Spondylitis is based on a combination of clinical symptoms, imaging studies (such as X-rays and MRI etc.), and genetic testing for HLA-B27.
Sound health is the need of the hour. Without a strong spine, a body fails to gain vitality. Ensure complete wellness by checking any issues pertaining to ankylosing spondylitis with Manipal TRUtest. Get treated on time to prevent any health crisis.
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Cancer
Know the Signs and Risks of Kidney Cancer
Cancer is a deadly disease and can affect any body part. The kidney is one region that might be affected by this disease. Kidney cells might develop into cancerous cells and form a tumor. They mostly appear in the kidney’s tubule lining. Kidney cancer, also known as renal cancer, often develops silently in its early stages. But early diagnosis of the tumour development helps prevent further complications. Fortunately, most cases can be identified early on. It allows prompt and effective treatment.
Causes of kidney cancer
Cancer develops as the cell’s DNA structure changes. Genetic mutation might cause abnormal cell development, resulting in the production of tumour cells. Inadequate treatment might cause further spreading of cancer. Usually, a single mass is formed in one or both kidneys. Later, it grows over time. It needs early diagnosis and prompt treatment. Understanding the symptoms and risks enables you to seek prompt treatment.
Understand the early signs
1. Persistent pain: Your back or side might experience intense pain. Usually, it is below the ribs.
2. Blood in urine: It is visible or microscopic. Colors other than normal require medical attention.
3. Sudden weight loss: Loss of weight without changing diet or exercising might be a sign of kidney cancer.
4. Swelling: You may experience swelling in your legs or ankles.
5. Lump in kidney area: You may feel a lump growing on the lower back of your kidney or the side.
6. Fever: You may experience a fever even after taking primary medicines.
7. Fatigue: Sleep might not be enough to feel relaxed. Tiredness may cause you to stop personal activities.
8. Other signs: These include anaemia, night sweats, or high blood pressure.
What are the risk factors?
- Obesity: If you are overweight, you might have developed the disease.
- Smoking: This factor contributes significantly to the disease.
- Genetic conditions: These include hereditary papillary renal carcinoma and von Hippel-Lindau conditions.
- Hypertension: If you suffer from high blood pressure, chances are you may have developed kidney cancer.
- Gender: Men suffer more than women.
- Age: If you are above sixty, you experience an increased risk of this disease.
- Chemical exposure: Some chemicals are harmful and could cause cancer. Hence, those working in the rubber, textile, and chemical industries are prone to it.
- Chronic kidney disease: It might develop into chronic kidney disease.
- Family history: If anyone in your family history has had this disease, there is a greater risk of you developing it.
- Lymphoma: If you experience lymphoma, you may suffer increased chances of developing cancer in the kidney area.
Prevent kidney cancer
Some effective steps can help reduce common risks. During the early stages, it doesn’t show any symptoms. However, visible signs are noticed as the tumour develops. Timely intervention is necessary to stop its further spread in the body.
Seek effective treatment
Kidney cancer is treatable, provided you are aware of the early signs and symptoms. Book a consultation with Manipal TRUtest if you feel any discomfort or notice symptoms. Prompt and accurate diagnosis can help you start early medication, which can help reduce pain and suffering.

Cancer
How Early Diagnosis Can Improve Cancer Treatment
Cancer treatment outcomes depend heavily on how early the disease is diagnosed. Detecting cancer in its early stages often leads to better survival rates, less invasive treatments, and improved quality of life. Early detection enables timely intervention even before the cancer has spread to other parts of the body, increasing the effectiveness of treatments like surgery and radiation therapy. Regular screenings, awareness of early warning signs, and access to diagnostic tests like colonoscopies, mammograms, and blood tests play a crucial role in identifying that cancer is at a manageable stage.
Methods of Early Diagnosis
Early detection of cancer relies on a variety of diagnostic tools and procedures that help identify the disease at its most treatable stage. Routine screenings such as mammograms, Pap smears, and colonoscopies are essential for detecting cancers like breast, cervical, and colorectal cancer before symptoms appear. Imaging techniques, including CT scans, MRIs, and ultrasounds, allow doctors to view the internal organs and tissues to identify abnormal growths and tumors. Biomarkers and genetic tests can detect early cellular changes and assess an individual's risk for certain cancers, aiding in personalized treatment planning. In cases where abnormal cells are found, biopsies are performed to confirm the diagnosis and determine the cancer type and stage.
Advantages of Early Detection
Early detection of cancer plays a vital role in improving treatment outcomes and long-term health. When cancer is identified at an early stage, it often results in higher survival rates, as the disease is more likely to be localized and treatable. Patients usually require less aggressive treatment, which means fewer side effects and complications compared to advanced-stage interventions. Additionally, early diagnosis can lead to lower treatment costs, as simpler therapies are often more cost-effective than complex, multi-step treatments required for later stages. Patients also benefit from faster recovery and a better quality of life, allowing them to return to normal routines more quickly and with less emotional and physical stress.
Barriers to Timely Diagnosis
Many people delay diagnosis due to fear, stigma, lack of awareness, or poor access to healthcare facilities. These barriers must be addressed through education and better healthcare infrastructure. Fear of cancer often leads individuals to ignore early symptoms, hoping they will resolve on their own. Social stigma can prevent open conversations, especially in communities where discussing illness is taboo. A lack of awareness about the importance of regular screenings and warning signs further contributes to late diagnosis. Moreover, in rural or economically weaker areas, people may not have access to quality healthcare services. Strengthening primary healthcare, training medical staff, and promoting community-based education can bridge these gaps effectively.
Encouraging Preventive Care
Promoting regular screenings, community awareness, and health literacy is essential. Government and healthcare systems must work together to ensure early detection becomes a norm.
Early cancer diagnosis saves lives. It allows for timely treatment, reduces complications, and improves outcomes for patients and their families. By identifying cancer in its initial stages, treatment is often more effective, less invasive, and less costly. It also helps preserve organ function, reduces emotional distress, and supports better long-term recovery and well-being.

Cancer
Empowering Women with Knowledge About Ovarian Cancer
Ovarian cancer is one of the major severe health concerns for women today. A silent interloper often called the "silent killer" because it also creeps in quietly, with symptoms so vague that they are often mistaken for common digestive or menstrual issues.
Bloating, pelvic discomfort, or feeling full too quickly may seem harmless, but when ignored, can lead to delayed diagnosis. However, “forewarned is forearmed.” With increased regular screenings and awareness, women can also rise against this hidden enemy. Knowledge is the power, and when combined with timely medical care, it can turn the tide.
Through the reliable health checkups, like those offered by Manipal TRUtest, women can also catch early signs, seek instant help, and beat the odds. Encouraging open conversations, supporting one another, and removing the fear surrounding cancer can truly save lives. It is time to break the silence, and empower every woman to prioritize her health because prevention is always better than a cure.
Understanding Ovarian Cancer
Ovarian cancer begins in the ovaries, the organs in charge of producing eggs in women. It often goes unnoticed until it spreads to other parts of the body. Common signs include:
- Frequent urination
- Pelvic pain
- Unexplained weight loss or fatigue
- Bloating or swelling in the abdomen
- Feeling full quickly while eating
If you experience these symptoms often, consult your doctor.
Risk Factors
Some women are more at risk than others. The main risk factors are:
- Family history of ovarian or breast cancer
- Endometriosis
- Genetic mutations (BRCA1 or BRCA2)
Knowing your risk helps you stay alert.
Importance of Regular Screening
The regular health checkups, especially after the age of 40, is important. At Manipal TRUtest, you can get access to affordable women's health checkups. These include ultrasound, CA-125 blood test, and consultation with specialists. Early detection leads to better treatment results.
Healthy Lifestyle for Prevention
The healthy lifestyle for prevention is
- Avoiding tobacco
- Discussing preventive options with your doctor if you have a family history
- Eating a healthy diet rich in fruits and vegetables
- Exercising regularly
Emotional Support Matters
The emotional support matters as a cancer diagnosis can be emotionally overwhelming. Women need support from family, friends, and professionals. Talking openly and joining support groups can help reduce anxiety and fear.
Take Action Today
Don't wait for symptoms to get worse. Take charge of your health. Book a women's wellness package at Manipal TRUtest and consult a healthcare expert. Remember, awareness, prevention, and early diagnosis are your best defense against ovarian cancer.