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Unite Against Ankylosing spondylitis - AS
Cancer
Sat Jul 22 2023
Ankylosing spondylitis (AS) is a severe, inflammatory ailment of the axial spine. Progressive spinal stiffness and chronic back pain are the most prevalent features of this illness. There is the involvement of the sacroiliac joints, spine, peripheral joints, entheses, and digits are quite characteristic. Physiologically impaired spinal movement, hip pain, posterior pain, postural abnormalities, peripheral arthritis, dactylitis, and enthesitis are generally related to ankylosing spondylitis.
This type of activity is instrumental in reviewing the assessment and management of ankylosing spondylitis and reflects the inter-professional team’s role in assessing and enhancing the care of patients suffering from this condition. The objectives are given below:
- Recognise the aetiology of ankylosing spondylitis.
- Mention the workup of a patient with ankylosing spondylitis
- Going through the management options which are available for ankylosing spondylitis.
- Put the inter-professional team strategies in a nutshell for enhancing care and outcomes in patients with ankylosing spondylitis.
HLA-B27 (Human Leukocyte Antigen B27) is a genetic marker that plays a significant role in the development of Ankylosing Spondylitis (AS).
It's important to understand that HLA-B27 testing alone cannot be used to diagnose Ankylosing Spondylitis, as not all individuals with HLA-B27 positivity develop the condition. Similarly, some individuals with Ankylosing Spondylitis do not have the HLA-B27 marker. Thus, the diagnosis of Ankylosing Spondylitis is based on a combination of clinical symptoms, imaging studies (such as X-rays and MRI etc.), and genetic testing for HLA-B27.
Sound health is the need of the hour. Without a strong spine, a body fails to gain vitality. Ensure complete wellness by checking any issues pertaining to ankylosing spondylitis with Manipal TRUtest. Get treated on time to prevent any health crisis.
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Cancer
How Early Cervical Cancer Is Detected Through Screening Tests
Cervical cancer is one of the few cancers that can frequently be prevented or identified early, long before symptoms appear. The answer is regular screening. A lot of women feel healthy and put off testing, not realizing that early cervical changes don’t usually produce any pain or even manifest outwardly. Knowing how cervical cancer can be found early through screening tests may help you take control of your health at the right time.
Why Early Detection of Cervical Cancer Is So Important
While cervical cancer typically progresses slowly, because of the abnormal changes in the cells that line the cervix. It can take years for these changes to become cancerous. Screening tests are meant to catch these abnormalities early, when treatment is easy, straightforward, and very effective.
Early detection helps to:
- Identify cell changes that may develop into cancer
- Diagnosing cervical cancer when it is in a highly curable stage
- Lessen the necessity for harsh treatments down the line
- Better long-term survival with improved quality of life
How Cervical Cancer Screening Works
The idea behind cervical cancer screening tests is to find abnormal cells in the cervix or to determine whether there are high-risk types of human papillomavirus that can lead to cancer. Such tests are fast, routine, and typically nonpainful.
Pap Smear Test: Detecting Abnormal Cervical Cells
A Pap smear is one of the most common cervical cancer screening tests. During testing, a healthcare provider gently removes some cells from the cervix and looks at them under a microscope.
What the Pap smear tests for:
- Precancerous changes in cervical cells
- Early-stage cervical cancer
- Infection or cervical inflammation
An abnormal result does not necessarily indicate cancer — but it does mean that you should follow up with a professional for further investigation, or to watch what’s happening.
HPV Test: Identifying the Root Cause Early
The vast majority of cervical cancers are caused by a prolonged infection with high-risk human papillomaviruses (HPV). High-risk strains include those that may lead to cancer, and an HPV test can detect the presence of these types of virus even before cell changes emerge.
This test can be particularly useful, as:
- Warts or other symptoms of HPV infection are not usually visible.
- It detects cancer risk weeks before cell changes
- And it assists physicians in determining how closely they need to be followed up
HPV testing is sometimes performed at the same time as a Pap smear for better screening.
Co-Testing: A More Comprehensive Screening Approach
For some age groups, doctors may recommend co-testing (both a Pap smear and an HPV test). This technique enhances the accuracy of early detection and minimizes the risks of false negatives.
Co-testing provides:
- Greater accuracy in detecting risk
- Relaxation of the screening interval for normal cholesteatoma results
- Better reassurance for patients
What Happens If Screening Results Are Abnormal?
An abnormal result of screening does not signal that cancer is present. Depending on the results, your doctor may suggest:
- Re-testing a few months later
- Colposcopy (a close look at the cervix)
- A biopsy of a sample cervical tissue
These subsequent steps can help verify whether treatment is necessary and when early intervention should start.
Who Should Get Screened and When?
Cervical cancer testing is suggested for women:
- Adult women from their early adulthood
- Those who are sexually active
- Individuals with weakened immune systems
- Those with a history of abnormal cervical tests
How often get screened varies by age, the type of test, and your previous test results, but regular screenings are crucial — even if you feel perfectly healthy.
Why Waiting for Symptoms Can Be Risky
Early-stage cervical cancer very rarely has any symptoms. The pain, bleeding, or discharge that rope worms may cause generally do not surface until the parasite has established itself, and treatment will be more complicated. Screening tests are made to find issues before you get sick, and by gosh, if Lee hadn’t had those regular testings, he wouldn’t be around this year, so routine testing is a lifesaver.
Staying on track with screening and following your doctor’s advice can significantly lower your risk for advanced cervical cancer.

Cancer
Because Every Woman Deserves More Tomorrows Start with Early Breast Cancer Diagnosis
Breast cancer remains one of the most common cancers affecting women worldwide. It not only impacts health but also affects families, emotions, and future plans. However, one fact gives hope: when breast cancer is detected early, the chances of successful treatment and survival increase greatly. That is why early diagnosis is considered the strongest shield against this disease. Every woman deserves a healthier tomorrow, and it begins with awareness, timely check-ups, and regular screenings.
Why Early Diagnosis Matters
Early diagnosis allows doctors to detect breast cancer before it spreads to other parts of the body. At this stage, treatment options are more effective, less invasive, and have better outcomes. Women who identify breast cancer early often require shorter treatment, face fewer complications, and have higher survival rates. On the other hand, late detection limits treatment choices and increases the risk of serious health consequences.
Common Signs to Watch For
Being aware of changes in the body is a powerful step toward early diagnosis. Some warning signs of breast cancer include:
- A lump or thickening in the breast or underarm
- Changes in breast shape or size
- Unexplained pain in the breast or nipple area
- Redness, dimpling, or skin irritation on the breast
- Unusual nipple discharge
While these symptoms may not always mean cancer, they should never be ignored. Consulting a doctor as soon as changes are noticed helps in a timely investigation.
The Power of Regular Screenings
Experts recommend annual mammograms for women over 40 and for those with a family history of breast cancer. A mammogram can detect tumors that are too small to be felt manually, offering a life-saving advantage.
Along with mammography, clinical breast exams, and monthly self-breast checks are essential tools every woman should adopt.
Know Your Risk Factors
Some factors that increase the risk of breast cancer include:
- Family history or genetic mutations (BRCA1, BRCA2)
- Age (risk rises after 40)
- Obesity and lack of exercise
- Smoking and excessive alcohol consumption
- Hormonal changes such as early menstruation or late menopause
While not all risks can be avoided, adopting a healthy lifestyle and staying alert to body changes can reduce vulnerability.
Empowerment Through Awareness
Taking charge of one’s health starts with awareness and regular preventive care.
Eat a balanced diet, stay active, manage stress, and go for regular health screenings. Talk openly with your doctor about risk factors and the right time to schedule tests. These small steps can create a big difference — for yourself and for those who love you.
A Promise for More Tomorrows
Breast cancer detected early is highly treatable — and often curable. Every screening, every check, and every act of awareness is a step toward saving lives.
Because every woman deserves not just today, but many more tomorrows filled with health, strength, and confidence.
Start early. Get screened. Stay aware.
Your tomorrow begins with today’s diagnosis.

Cancer
Stages of Ovarian Cancer and Available Treatment Options
Ovarian cancer is one of the most serious cancers affecting women. It begins in the ovaries, the small organs responsible for producing eggs and female hormones. Detecting ovarian cancer at an early stage is often difficult because symptoms are vague and can resemble other conditions. However, knowing the stages of ovarian cancer and the treatment options available can help patients and families make informed decisions.
Stages of Ovarian Cancer
Ovarian cancer is classified into four main stages, based on how far the disease has spread in the body.
Stage I
In this stage, the cancer is limited to one or both ovaries. It has not spread to nearby organs or distant parts of the body. Symptoms are often mild, such as bloating, pelvic pain, or changes in urination. Stage I is the most treatable stage because the cancer is confined.
Stage II
At this stage, the cancer has spread beyond the ovaries to nearby structures in the pelvis, such as the uterus, fallopian tubes, or bladder. Symptoms may become more noticeable, including abdominal pain, swelling, or digestive issues. Treatment is more complex than Stage I but still offers a good chance of control.
Stage III
Stage III ovarian cancer means the disease has spread outside the pelvis to the lining of the abdomen (peritoneum) or nearby lymph nodes. This is the most common stage at diagnosis. Symptoms may include severe abdominal swelling, difficulty eating, and fatigue. It requires intensive treatment, as the cancer has already reached wider areas of the body.
Stage IV
This is the most advanced stage, where the cancer has spread to distant organs such as the liver, lungs, or spleen. Patients may experience weight loss, chest pain, difficulty breathing, and extreme fatigue. Stage IV is the hardest to treat, but therapies can still improve survival and quality of life.
Available Treatment Options
Treatment for ovarian cancer depends on the stage, overall health of the patient, and specific type of ovarian cancer. The main approaches include:
- Surgery
Surgery is often the first step in treating ovarian cancer. The goal is to remove as much of the tumor as possible. In early stages, surgery may involve removing one or both ovaries and sometimes the uterus and fallopian tubes. In advanced stages, extensive surgery may be required to remove cancer from other affected areas in the abdomen.
- Chemotherapy
Chemotherapy uses powerful drugs to kill cancer cells or stop them from growing. It is usually given after surgery to target any remaining cancer cells. In advanced cases, chemotherapy may also be given before surgery to shrink the tumor.
- Targeted Therapy
Targeted therapy focuses on specific genetic changes or proteins that allow cancer to grow. For example, PARP inhibitors are a newer class of drugs that help treat certain types of ovarian cancer, especially in women with BRCA gene mutations.
- Hormone Therapy
Hormone therapy may be used in some cases to block hormones that help cancer grow. It is less common but can be helpful for specific subtypes of ovarian cancer.
- Radiation Therapy
Radiation is not commonly used for ovarian cancer but may be recommended in rare cases to shrink tumors or relieve symptoms.
Hope through Early Detection
Ovarian cancer remains a formidable disease, but early detection dramatically improves survival rates. Women should never ignore persistent bloating, pelvic pain, or digestive changes. Regular health screenings and diagnostic imaging help identify potential issues before they progress.
At Manipal TRUtest, our advanced diagnostic imaging and laboratory services support early detection and accurate monitoring of ovarian and other cancers. With precise results, expert care, and compassionate service, we help women take proactive steps toward better health and timely treatment.